The relation of body mass index, demographic and health-related variables to length of stay for patients at an acute rehabilitation hospital after total hip arthroplasty

Obesity is a growing public health concern world-wide. At the same time, knee and hip replacements are becoming an increasingly regular treatment for osteoarthritis. There are conflicting reports in the literature as to what extent body mass affects the length of stay (LOS) of patients undergoing total hip replacements. This chart review aims at examining the ­relationship between body mass index (BMI), demographic and health-related variables, and LOS. The retrospective chart review of one acute inpatient rehabilitation facility involved n = 119 patients. There was no significant association between LOS and body mass index (BMI), confirming earlier results. Insurance payer type (Medicare vs private) was statistically significant related to LOS. Moreover, there was a trend for the potential influence of race/ethnic patient background on LOS with Caucasians having shorter hospital stays. © 2010 Greenberg and Kroll, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.</p

Mixing of pseudoscalar mesons and isospin symmetry breaking

Mixing of the pseudoscalar mesons is discussed in the quark-flavor basis with the hypothesis that the basis decay constants follow the pattern of particle state mixing. The divergences of the axial vector currents which embody the axial vector anomaly, combined with this hypothesis provide a calculational scheme for the parameters describing the mixing of the pion, eta and eta' mesons. Phenomenological applications of this mixing scheme are presented with particular interest focussed on isospin symmetry breaking in QCD estimated as eta and eta' admixtures to the pion. In contrast to previous work a possible difference in the basis decay constants f_u and f_d is considered and consequences of this potentially large effect on the strength of isospin symmetry breaking is discussed.Comment: 10 pages, (using LATEX with w-ijmpa.sty), invited talk presented at MESON 2004, 8th Intern. Workshop on Meson Production, Properties and Interaction

Mixing and Decay Constants of Pseudoscalar Mesons: The Sequel

We present further tests and applications of the new eta-eta' mixing scheme recently proposed by us. The particle states are decomposed into orthonormal basis vectors in a light-cone Fock representation. Because of flavor symmetry breaking the mixing of the decay constants can be identical to the mixing of particle states at most for a specific choice of this basis. Theoretical and phenomenological considerations show that the quark flavor basis has this property and allows, therefore, for a reduction of the number of mixing parameters. A detailed comparison with other mixing schemes is also presented.Comment: 9 page

Perturbative and non-perturbative QCD corrections to wide-angle Compton scattering

We investigate corrections to the handbag approach for wide-angle Compton scattering off protons at moderately large momentum transfer: the photon-parton subprocess is calculated to next-to-leading order QCD and contributions from the generalized parton distribution E} are taken into account. Photon and proton helicity flip amplitudes are non-zero due to these corrections which leads to a wealth of polarization phenomena in Compton scattering. Thus, for instance, the incoming photon asymmetry or the transverse polarization of the proton are non-zero although small.Comment: 19 pages, 9 figures (using LATEX with epsfig

Patient-reported outcome measures for chronic obstructive pulmonary disease: the exclusion of people with low literacy skills and learning disabilities

&lt;p&gt;Background: Patient-reported outcome measures (PROMs) are intended to reflect outcomes relevant to patients. They are increasingly used for healthcare quality improvement. To produce valid measures, patients should be involved in the development process but it is unclear whether this usually includes people with low literacy skills or learning disabilities. This potential exclusion raises concerns about whether these groups will be able to use these measures and participate in quality improvement practices.&lt;/p&gt; &lt;p&gt;Methods: Taking PROMs for chronic obstructive pulmonary disease (COPD) as an exemplar condition, our review determined the inclusion of people with low literacy skills and learning disabilities in research developing, validating, and using 12 PROMs for COPD patients. The studies included in our review were based on those identified in two existing systematic reviews and our update of this search. Results People with low literacy skills and/or learning disabilities were excluded from the development of PROMs in two ways: explicitly through the participant eligibility criteria and, more commonly, implicitly through recruitment or administration methods that would require high-level reading and cognitive abilities. None of the studies mentioned efforts to include people with low literacy skills or learning disabilities.&lt;/p&gt; &lt;p&gt;Conclusion: Our findings suggest that people with low literacy skills or learning disabilities are left out of the development of PROMs. Given that implicit exclusion was most common, researchers and those who administer PROMs may not even be aware of this problem. Without effort to improve inclusion, unequal quality improvement practices may become embedded in the health system.&lt;/p&gt

Linear model for fast background subtraction in oligonucleotide microarrays

One important preprocessing step in the analysis of microarray data is background subtraction. In high-density oligonucleotide arrays this is recognized as a crucial step for the global performance of the data analysis from raw intensities to expression values. We propose here an algorithm for background estimation based on a model in which the cost function is quadratic in a set of fitting parameters such that minimization can be performed through linear algebra. The model incorporates two effects: 1) Correlated intensities between neighboring features in the chip and 2) sequence-dependent affinities for non-specific hybridization fitted by an extended nearest-neighbor model. The algorithm has been tested on 360 GeneChips from publicly available data of recent expression experiments. The algorithm is fast and accurate. Strong correlations between the fitted values for different experiments as well as between the free-energy parameters and their counterparts in aqueous solution indicate that the model captures a significant part of the underlying physical chemistry.Comment: 21 pages, 5 figure

Ising magnets with mobile defects

Motivated by recent experiments on cuprates with low-dimensional magnetic interactions, a new class of two-dimensional Ising models with short-range interactions and mobile defects is introduced and studied. The non-magnetic defects form lines, which, as temperature increases, first meander and then become unstable. Using Monte Carlo simulations and analytical low- and high-temperature considerations, the instability of the defect stripes is monitored for various microscopic and thermodynamic quantities in detail for a minimal model, assuming some of the couplings to be indefinitely strong. The robustness of the findings against weakening the interactions is discussed as well

Resummed Green-Kubo relations for a fluctuating fluid-particle model

A recently introduced stochastic model for fluid flow can be made Galilean invariant by introducing a random shift of the computational grid before collisions. This grid shifting procedure accelerates momentum transfer between cells and leads to a collisional contribution to transport coefficients. By resumming the Green-Kubo relations derived in a previous paper, it is shown that this collisional contribution to the transport coefficients can be determined exactly. The resummed Green-Kubo relations also show that there are no mixed kinetic-collisional contributions to the transport coefficients. The leading correlation corrections to the transport coefficients are discussed, and explicit expressions for the transport coefficients are presented and compared with simulation data.Comment: 4 pages including 4 figures, submitted to PRE Rapid Com